2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Dipeptidyl Peptidase
  5. Dipeptidyl Peptidase Isoform
  6. Dipeptidyl Peptidase Antagonist

Dipeptidyl Peptidase Antagonist

Dipeptidyl Peptidase Antagonist (1):

Cat. No. Product Name Effect Purity
  • HY-111282
    MK-789
    		Antagonist
    MK-789 is a competitive reversible inhibitor of dehydropeptidase I (DHP-I). MK-789 competitively blocks the entry of N-formimidoylthienamycin into proximal tubular cells, thereby inhibiting its renal metabolism. MK-789 shifts the renal excretion pathway of N-formimidoylthienamycin to glomerular filtration only, increasing its urinary recovery rate and renal clearance. MK-789 is applicable to studies on renal metabolism and pharmacokinetics.